Jeffrey Price
- Research Assistant Professor, Department of Food Science & Technology
- Associate Director, Nebraska Gnotobiotic Mouse Program
jprice23@unl.edu
402-937-07-09
Dr. Price's research background is mainly in regulation of immune responses, especially related to dendritic cells and T cells. I am currently using that work in projects related to the mouse and human microbiome. Our gnotobiotic mouse facility is currently examining the role of the microbiome in diseases ranging from inflammatory bowel disease to food allergies.
Featured Publications
Liu X, Clemens DL, Grunkemeyer JA, Price JD, O'Connell K, Chapman NM, Storz P, Wen H, Cox JL, Reid WL, Hollingsworth MA, Thayer S. Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis. Sci Rep. 2019 Jul 23;9(1):10656. doi: 10.1038/s41598-019-46933-y. PMID: 31337812; PMCID: PMC6650496.
Decalf J, Tarbell KV, Casrouge A, Price JD, Linder G, Mottez E, Sultanik P, Mallet V, Pol S, Duffy D, Albert ML. Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post-translational modification: prospective placebo-controlled clinical studies. EMBO Mol Med. 2016 Jun 1;8(6):679-83. doi: 10.15252/emmm.201506145. PMID: 27137491; PMCID: PMC4888857.
Price JD, Hotta-Iwamura C, Zhao Y, Beauchamp NM, Tarbell KV. DCIR2+ cDC2 DCs and Zbtb32 Restore CD4+ T-Cell Tolerance and Inhibit Diabetes. Diabetes. 2015 Oct;64(10):3521-31. doi: 10.2337/db14-1880. Epub 2015 Jun 12. PMID: 26070317; PMCID: PMC4587633.
Price JD, Tarbell KV. The Role of Dendritic Cell Subsets and Innate Immunity in the Pathogenesis of Type 1 Diabetes and Other Autoimmune Diseases. Front Immunol. 2015 Jun 15;6:288. doi: 10.3389/fimmu.2015.00288. PMID: 26124756; PMCID: PMC4466467.
Price JD, Beauchamp NM, Rahir G, Zhao Y, Rieger CC, Lau-Kilby AW, Tarbell KV. CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L. J Leukoc Biol. 2014 Feb;95(2):325-36. doi: 10.1189/jlb.0113013. Epub 2013 Sep 30. PMID: 24082013; PMCID: PMC3896656.