Kaustav Majumder

The overarching goal of Dr. Majumder’s laboratory is to understand the impact of dietary proteins and peptides on human health, and to develop dietary-peptide-based functional foods for the prevention and treatment of hypertension and associated cardio-metabolic disorders. The research program targets to delineate the mechanisms of action of dietary bioactive proteins/peptides and explores their underlying signaling mechanism to modulate the pathogenesis of cardiac diseases. Presently our work focuses on how dietary peptides modulates the gastro-renal axis to regulate the blood pressure. The research program also aims to identify the biomarkers and the genetic alteration happen due to the intervention of bioactive food proteins/peptides. Additionally, Dr. Majumder’s laboratory also explore the potential of different food processing techniques (i.e., enzymatic digestion, fermentation) to produce health beneficial bioactive peptides from various plant-based proteins.

Featured publications

  • Mine, Y., Jin, Y., Zhang, H., Rupa, P., Majumder, K., Sukurai., T., Taniguchi, Y., Takagaki, R., Watanabe, H., Mitsuzumi, H. (2019). Prophylactic effects of isomaltodextrin in a Balb/c mouse model of egg allergy. npj Science of Food, 3: 23.
  • Xing, L., Zhang, H., Majumder, K., Zhang, W., Mine, Y. (2019). γ‑glutamylvaline prevents low-grade chronic inflammation via activation of a calcium-sensing receptor pathway in 3T3-L1 mouse adipocytes. Journal of Agricultural and Food Chemistry, 67 (30): 8361-8369. 
  • Chakrabarti, S., Guha, S., Majumder, K. (2018). Food-Derived bioactive peptides in human health: challenges and opportunities. Nutrients, 10: 1738.
  • Majumder, K., Liang, G., Chen, Y., Guan, L., Davidge, S. T. & Wu, J. (2015). Egg ovotransferrin-derived ACE inhibitory peptide IRW increases ACE2 but decreases proinflammatory genes expression in mesenteric artery of spontaneously hypertensive rats. Molecular Nutrition and Food Research, 59: 1735–1744.
  • Majumder, K., Chakrabarti, S., Morton, J. S., Panahi, S., Kaufman, S., Davidge, S. T. & Wu, J. (2015). Egg-derived ACE-inhibitory peptides IQW and LKP reduce blood pressure in spontaneously hypertensive rats. Journal of Functional Foods 13: 50–60.