- Assistant Professor, Department of Food Science and Technology
The overarching goal of Dr. Majumder’s laboratory is to understand the impact of dietary proteins and peptides on human health, and to develop dietary-peptide-based functional foods for the prevention and treatment of hypertension and associated cardio-metabolic disorders. The research program targets to delineate the mechanisms of action of dietary bioactive proteins/peptides and explores their underlying signaling mechanism to modulate the pathogenesis of cardiac diseases. Presently our work focuses on how dietary peptides modulates the gastro-renal axis to regulate the blood pressure. The research program also aims to identify the biomarkers and the genetic alteration happen due to the intervention of bioactive food proteins/peptides. Additionally, Dr. Majumder’s laboratory also explore the potential of different food processing techniques (i.e., enzymatic digestion, fermentation) to produce health beneficial bioactive peptides from various plant-based proteins.
- Mine, Y., Jin, Y., Zhang, H., Rupa, P., Majumder, K., Sukurai., T., Taniguchi, Y., Takagaki, R., Watanabe, H., Mitsuzumi, H. (2019). Prophylactic effects of isomaltodextrin in a Balb/c mouse model of egg allergy. npj Science of Food, 3: 23.
- Xing, L., Zhang, H., Majumder, K., Zhang, W., Mine, Y. (2019). γ‑glutamylvaline prevents low-grade chronic inflammation via activation of a calcium-sensing receptor pathway in 3T3-L1 mouse adipocytes. Journal of Agricultural and Food Chemistry, 67 (30): 8361-8369.
- Chakrabarti, S., Guha, S., Majumder, K. (2018). Food-Derived bioactive peptides in human health: challenges and opportunities. Nutrients, 10: 1738.
- Majumder, K., Liang, G., Chen, Y., Guan, L., Davidge, S. T. & Wu, J. (2015). Egg ovotransferrin-derived ACE inhibitory peptide IRW increases ACE2 but decreases proinflammatory genes expression in mesenteric artery of spontaneously hypertensive rats. Molecular Nutrition and Food Research, 59: 1735–1744.
- Majumder, K., Chakrabarti, S., Morton, J. S., Panahi, S., Kaufman, S., Davidge, S. T. & Wu, J. (2015). Egg-derived ACE-inhibitory peptides IQW and LKP reduce blood pressure in spontaneously hypertensive rats. Journal of Functional Foods 13: 50–60.